There is research that links more potent cannabis, including skunk, to THC-related changes in the brain, among daily users at least.
That we have such a large and growing community of frequent users is a tribute not to evidence, but to hype.
Suddenly we’re missing obvious warning signs, ignoring key markers of danger, or simply deciding to take a leap of faith at exactly the wrong moment.
Research admittedly takes a long time, including the need for replication, and patients in clinical programs aren’t necessarily willing to wait.
Suppose we could develop cognitive techniques and train the patient to use them whenever symptoms reappeared?
The relative importance of set and setting suggests that the environment in an LSD experience should be carefully controlled.
I think the problem is I have read the research, and it didn’t confirm the claims made on its behalf.