It can be flagrant or subtle, but damage it will be. Sadly, the drinker is usually the last one to become aware of it. In fact, many never do.
Cannabis doesn’t replace opioids the way methadone or buprenorphine do. There’s no antagonist effect as with naloxone or naltrexone.
The list of deaths from the practice is long and oddly prestigious, featuring celebs such as John Belushi and Chris Farley, among many others.
Now, with the introduction of fentanyl and carfentanil, the decision to inject heroin or cocaine can easily result in a fatality.
Then there are the users who seek to overcome their own elevated tolerance, which interferes with ordinary drug-taking, by simultaneously consuming a second substance of the same general effect
It’s easy to take too much. When that happens, a coma may result. After waking, it’s common to have suffered memory loss.
Still, if the epidemic is already 28 years old, then how much more effective would these steps have been if they had been initiated way back when?