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The goal is to eventually develop an objective scale by which pain can be measured not by self-report, but by neuroimaging.

As control erodes, the drinker redoubles efforts to regain it. Some resort to “white-knuckle” abstinence, giving up alcohol for a while, just to prove to themselves or someone else that they can.

As the article points out, it’s possible to make use of the flashlight on your cellphone for the necessary illumination.

Once such substances get a foothold in a region, they’re extremely hard to eradicate.

My concern is that these same hallucinogens have a pronounced tendency to escape the research environment and find their way out into the streets

…as one judge told me at a conference: “no matter how many jails you build, judges will fill them. It’s the easiest way to make this someone else’s problem, instead of ours.”

Much of the chronic user’s life is taken up by anxiety, about where future doses will come from.

Some approaches are better than others at helping an individual identify what works for them in understanding their disease and establishing a stable recovery.

So if some enterprising MD or PhD were to show with a proposal for research designed to prove that drinking has definite health benefits, the industry will throw money at it.

“All my friends drink,” someone says. There’s a reason for that.